Adinizer Fat Processing
From a single harvest, prepare smooth, injectable microfat in 3–5 passes, then further refine it into nanofat or an ASC-enriched preparation—with less processing and lower pressure.
One-Harvest. Multiple Preparations.
The Fat Continuum
The Adinizer® platform doesn’t create a single fat product. From one harvest, physicians can select an adipose preparation tailored to the patient’s clinical and biologic needs. Adipose tissue provides both structural support and biologic signaling—and how it is harvested, mechanically processed, and micronized influences the balance between these functions.
As the preparation becomes finer, its primary clinical role progresses along a continuum:
Structure → Stromal Tissue Scaffold → Signaling Catalyst
Larger preparations emphasize volume and structural architecture. Finer preparations allow more precise placement while placing greater emphasis on stromal tissue elements, extracellular matrix, and the signaling environment. These are not rigid categories—each preparation retains both structural and biologic characteristics, with the balance shifting according to the mechanical processing pathway and clinical application.
Microfat grafts primarily serve a structural and volumetric role, while progressively smaller preparations shift toward biologic and regenerative function.
*Disc selection and delivery gauge depend on harvest method, tissue characteristics, and preparation protocol. The Adinizer pathway can be adjusted to the tissue and intended application.
MICROFAT
What It Is
Adinized Microfat is a precision-sized adipose preparation composed of smaller, more uniform tissue parcels while preserving adipocyte structure and native tissue architecture. Reducing parcel size increases the surface-area-to-volume ratio and shortens diffusion distances, supporting perfusion, graft integration, and volume retention.
Applications and Uses
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Mid-to-deep facial volume restoration and contouring
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Dorsal hand rejuvenation and soft-tissue coverage
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Secondary corrections, touch-ups, and contour transitions
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Localized reconstructive defects and tissue asymmetries
Disc Pathway
2400µm → 1200µm → Up to 19G*
MACROFAT
What It Is
Macrofat is a larger-parcel autologous adipose tissue graft that preserves mature adipocytes within their native extracellular matrix and stromal architecture. Its larger parcel size makes it primarily suited for volume restoration, contouring, cushioning, and deep structural support.
Applications and Uses
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Breast augmentation, contour correction, and reconstruction
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Gluteal and body-contouring procedures
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Deep facial volume and structural contour
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Traumatic, congenital, and postoperative soft-tissue defects
Disc Pathway
2400µm → Macrofat → Up to 17G*
SCAFFOLDING- MFAT
What It Is
Scaffolding Microfat is a stromal-rich preparation designed for targeted soft-tissue support, contour refinement, and placement with delicate anatomical planes. It reduces mature adipocyte predominance while preserving extracellular matrix and associated stromal elements, enabling delivery through approximately 21–23G. It provides limited structural volume while functioning primarily as a tissue-preserving biologic scaffold.
Applications and Uses
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Targeted placement in superficial and delicate tissue planes
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Scarred, fibrotic, irradiated, or otherwise compromised tissue
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Orthobiologic and musculoskeletal applications
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Biocellular protocols, including combination with PRP
Disc Pathway
2400µm → 1200µm → 600µm 21-23G*
ADINIZED NANOFAT
What It Is
Adinized Nanofat is a finely processed autologous adipose tissue preparation intended primarily for regenerative rather than volumetric use. Designed for fine-gauge delivery, it prioritizes cellular signaling, tissue remodeling, and regenerative support rather than conventional volume restoration. Progressive mechanical processing reduces mature adipocytes while retaining stromal, vascular, and extracellular components associated with tissue remodeling and repair.
Applications and Uses
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Facial and periorbital rejuvenation for fine lines and wrinkles, skin texture, tone, pigmentation
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Acne, surgical, traumatic, burn, and fibrotic scars
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Chronic wounds and compromised or irradiated tissue
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Hair restoration and regenerative scalp procedures
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Vulvovaginal, intimate-wellness, and lichen sclerosus protocols
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Biocellular and orthobiologic applications, including combination with PRP
Disc Pathway
2400µm → 1200µm → 600µm → 400µm
Up to 27G*
MACROFAT
Structural Preparation
Up to 17G
What it is
Macrofat is a larger-parcel autologous adipose tissue graft that preserves mature adipocytes within their native extracellular matrix and stromal architecture. Its larger parcel size makes it primarily suited for volume restoration, contouring, cushioning, and deep structural support.
Clinical Applications
-
Breast augmentation, contour correction, and reconstruction
-
Gluteal and body-contouring procedures
-
Deep facial volume and structural contour
-
Traumatic, congenital, and postoperative soft-tissue defects
Disc Pathway
2400µm → Up to 17G*
MICROFAT
Structural Preparation
18 - 20G
What it is
Adinized Microfat is a precision-sized adipose preparation made of smaller, more uniform tissue parcels that preserve adipocyte structure and native tissue architecture. Smaller parcels increase the surface-area-to-volume ratio and shorten diffusion distances, supporting perfusion, graft integration, and volume retention.
Clinical Applications
-
Mid-to-deep facial volume restoration and contouring.
-
Dorsal hand rejuvenation and soft-tissue coverage.
-
Secondary corrections, touch-ups, and contour transitions.
-
Localized reconstructive defects and tissue asymmetries.
Disc Pathway
2400µm → 1200µm → Up to 19G*
SCAFFOLDING - FAT
Structural Preparation
21 - 23G
What it is
Scaffolding fat is a stromal-rich preparation designed for targeted soft-tissue support, contour refinement, and placement with delicate anatomical planes. It reduces mature adipocyte predominance while preserving extracellular matrix and associated stromal elements, enabling delivery through approximately 21–23G. It provides limited structural volume while functioning primarily as a tissue-preserving biologic scaffold.
Clinical Applications
-
Targeted placement in superficial and delicate tissue planes
-
Scarred, fibrotic, irradiated, or otherwise compromised tissue
-
Orthobiologic and musculoskeletal applications
-
Biocellular protocols, including combination with PRP
Disc Pathway
2400µm → 1200µm → 600µm 21-23G*
NANOFAT
Regenerative Preparation
Up to 27G*
What it is
Adinized Nanofat is a finely processed autologous adipose tissue preparation intended primarily for regenerative rather than volumetric use. Designed for fine-gauge/meso delivery, it prioritizes cellular signaling, tissue remodeling, and regenerative support over conventional volume restoration. Sequential mechanical blade-cutting removes mature adipocytes while retaining stromal, vascular, and extracellular components associated with tissue remodeling and repair.
Clinical Applications
-
Facial and periorbital rejuvenation for fine lines and wrinkles, skin texture, tone, and pigmentation.
-
Acne, surgical, traumatic, burn, and fibrotic scars.
-
Chronic wounds and compromised or irradiated tissue.
-
Hair restoration and regenerative scalp procedures.
-
Vulvovaginal, intimate-wellness, and lichen sclerosus protocols.
-
Biocellular and orthobiologic applications, including combination with PRP.
Disc Pathway
2400µm → 1200µm → 600µm → 400µm Up to 27G*
ASC Preparations
Purified Nanofat · mSVF · TOST · ECM Gel
Up to 27G*
What it is
Adinized nanofat can undergo a second centrifugation to separate and concentrate its tissue layers. Clinicians can retain the layers together as purified nanofat or select specific fractions, such as TOST for a more concentrated stromal preparation.
Why Refine
Processing fat into 27G* nanofat releases additional free oil and cellular debris. A second centrifugation separates free oil and debris from the retained tissue and concentrates its components into a smaller volume
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Remove oil and debris: A second centrifugation separates the processed tissue into visible layers so you can remove unwanted material.
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Concentrate what remains: Removing excess fluid reduces the delivery volume and concentrates the retained stromal tissue components.
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Choose the fraction: Use the retained layers together as purified nanofat, or select the stromal aggregate and cell-containing fractions based on intended use.
Biologic Purpose
The goal is to deliver autologous stromal components, preserved extracellular matrix, and their signaling activity where they are needed. Selecting and concentrating the fractions gives clinicians options for tissue support and biostimulation, including hair restoration and other biocellular applications.
Disc Pathway
2400µm → 1200µm → 600µm → 400µm
PLUS Refinement Piston Lock Up to 27G*
What's in a Name?
The terminology used to describe fat micronizing—including macrofat, millifat, MFAT, microfat, nanofat, tSVF, mSVF, TOST, SVM, and many other names—is not standardized in the medical literature or industry.
These terms can represent preparations with very different tissue characteristics, processing methods, delivery requirements, and intended clinical roles.
With the Adinizer, these preparations are organized around a few clinically relevant characteristics: injectable delivery gauge, structural versus regenerative preparation, and the intended clinical and biological application.
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